De jaarlijkse griepprik wordt voortaan geproduceerd volgens eenzelfde methode als de Corona-vaccinatie: met mRNA-technologie.

De effectiviteit van de jaarlijkse griepprik kan een stuk beter, zo meent de farmaceutische industrie.

Unlike other vaccines, influenza shots are administered yearly, yet offer generally lower protection than most routinely recommended vaccines, from as low as 10 percent to as high as 60 percent. This season’s flu jab was only 16 percent effective, according to the Centers for Disease Control and Prevention (CDC).

Er wordt al een hele tijd gewerkt aan een universeel griepvaccin, maar tot op heden zonder succes:

Scientists had hoped to develop a universal flu vaccine that could fight against many strains of the flu and be given every five or 10 years, eliminating the need for annual shots. They said it could take eight to 10 years for the universal flu vaccine to be available, but over a decade later, the research did not bear fruit.

Men hoopt de doorgaans teleurstellende resultaten te kunnen verbeteren door toepassing van de mRNA-technologie.

Now, major pharmaceuticals are hoping to change the shot’s underwhelming protection and the current flu manufacturing process with the messenger RNA (mRNA) technology platform.
If the companies are able to succeed in this, the “new flu jabs could prove lucrative or help maintain standing in a global market projected to exceed US$10 billion by decade’s end,” according to an article published in Nature.

In de USA is de jaarlijkse griepprik een belangrijke markt:

Dr. Robert Malone, who helped invent the mRNA vaccine technology, said that flu shots are a “significant commercial market in the United States” that is annually recommended to “drive a market need so that the manufacturing plants can be kept running and certified” in the possibility that an outbreak similar to the 1918 influenza pandemic should occur.
“The government wants to be able to ensure that they always have enough influenza capacity in case the bad thing happens,” Malone told The Epoch Times. “So the way they do that is they create market incentives for manufacturers to produce seasonal influenza vaccines, even though we don’t really need them.”

Er wordt dus stevig aan verdiend:

Fortune Business Insights, offering market studies and consultation services, reported that the flu vaccines generated about $5.86 billion in 2020 and $6.59 billion globally in 2021, and is projected to grow to $10.73 billion in 2028 at a CAGR [compound annual growth rate] of 7.2 percent.

De Corona-tijd heeft dit initiatief op gang gebracht:

“The coronavirus pandemic naturally impacted the routine immunization programs and campaigns conducted worldwide in developing and developed countries,” the company said in its report. “However, Flu vaccination rates have gone up considerably during the pandemic owing to factors such as push from health experts/health departments as well as extension/expansion of various government programs that provide free vaccination against the flu.”
Seqirus, one of the largest manufacturers of flu shots in the world and owned by CSL Limited, experienced a sales growth of its vaccines despite the pandemic, with the company’s chief executive officer reporting (pdf) total revenue of “over $1.7 billion, up 30% at constant currency” for the fiscal year 2021 that was “driven by the very strong sales growth in seasonal influenza vaccines of some 41%.”

De betrokken producenten zijn al van start gegaan:

Differentiating itself from its competitors, Seqirus is developing flu vaccine candidates based on the next generation of mRNA technology, self-amplifying messenger RNA (sa-mRNA).
Like mRNA vaccines that instruct the cells in the body to make a protein that stimulates the immune response to build up immunity, sa-mRNA also “instructs the body to replicate mRNA, amplifying the amount of protein made.”
“This could enable vaccine manufacturers to potentially develop more effective vaccines with a smaller dosage and with lower rates of reactogenicity, underscoring the application in both pandemic and seasonal settings,” the vaccine maker announced in a press release in August 2021.
Seqirus said it would begin clinical trials of its seasonal and pandemic flu vaccine candidates in the second half of 2022.
Pfizer, Moderna, and Sanofi began testing their mRNA flu vaccines in adults 18 and older in 2021, while Curevac announced last month it was conducting a small Phase 1 trial in Panama.

Dat u weet waarmee men u dit najaar wil inspuiten:

Moderna released interim data for the Phase 1 trial of its quadrivalent (four-strain) seasonal flu vaccine candidate, mRNA-1010 in December 2021, and announced that its two-dose vaccine produced robust antibody titers with “no significant safety concerns” observed, even at the lowest dose of 50 micrograms.

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